PDP1 Functions Downstream of the Circadian Oscillator to Mediate Behavioral Rhythms
نویسندگان
چکیده
منابع مشابه
PDP1 Functions Downstream of the Circadian Oscillator to Mediate Behavioral Rhythms
The Drosophila circadian oscillator is composed of autoregulatory period/timeless ( per/tim) and Clock (Clk) feedback loops that control rhythmic transcription. In the Clk loop, CLOCK-CYCLE heterodimers activate vrille (vri) and PAR domain protein 1 (Pdp1 ) transcription, then sequential repression by VRI and activation by PDP1 mediate rhythms in Clk transcription. Because VRI and PDP1 bind the...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2007
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.4870-06.2007